Endocrine Abstracts

Background: Bariatric surgery has contributed to a large spectrum of presentations of hypoglycaemia. Dumping syndrome caused by food reaching the duodenum rapidly is associated with abdominal pain, bloating and diarrhoea as well as vasogenic symptoms of tachycardia and flushing. Hypoglycaemia may occur as a late sign of dumping 1–3 hours after a meal. In contrast, post-gastric bypass reactive hypoglycaemia is thought to result from discordance between blood glucose circul...

Pregnancy and lactation-associated osteoporosis (PAO) is a rare syndrome of spontaneous fragility fractures, most commonly vertebral, occurring in late pregnancy or lactation. The aetiology and pathogenesis of this osteoporosis are unknown, and early diagnosis and management are essential because of the severity of the morbidity associated with these fractures. The management includes cessation of breastfeeding, use of specific osteoporosis drugs, and adequate analgesia.<p...

Background: During the first wave of the COVID pandemic a large proportion of diabetic clinics and services were reduced or postponed, combined with a move to telephone consultations for GPs. Diabetic nurse specialists were also re-deployed from regular inpatient services. Additionally, patients were reluctant to seek out healthcare services either due to the risk of contracting COVID or not wanting to place unnecessary stress on the healthcare services....

Background: Poor diabetes control is associated with increased risks in all types of hospital admission. Admission into hospital among children and young people with diabetes places a large burden on the NHS resources. For example the cost of a DKA stay per patient is £20641.Introduction: We analysed the paediatric admissions to hospital of those in T1DM. Our objective was to compare our type of hospital admissions to the national paediat...

Background: Recent studies have reported a correlation between the increase in incidence of Type 1 Diabetes (T1DM) in children and young people (CYP) and SARS-COVID19 Infection.Aims and objectives: To study if there is an increase in TIDM incidence in CYP (aged 0-18yrs) post-covid19 (April 2020- March 2021) in East of England (EOE) region compared to previous years (April 2018- March 2020). To identify a correlation between T1DM incidence and the UK COVI...

Introduction: Primary hyperaldosteronism (PA) can affect up to 10% of patients with hypertension. Adrenal vein sampling (AVS) is used to distinguish between unilateral and bilateral aldosterone production. However, it is invasive, technically challenging and is only performed in a limited number of centres. This audit aimed to evaluate the effectiveness of AVS in informing the management of PA in a large teaching hospital.Methods: A retrospective audit o...

Background: Adrenal incidentalomas are discovered unexpectedly and with increasing frequency on cross-sectional imaging acquired for reasons unrelated to adrenal dysfunction. Whilst the majority are non-functioning, literature suggests there is an increased risk of malignancy for adrenal incidentalomas above 4 cm. American guidelines advising resection of all incidentalomas above 4 cm were established without strong evidence whilst European guidelines adopt a more pragmatic ap...

A 34 year old male, previously healthy nightclub doorman presented with 2 years of reduced libido, fatigue, hot flushes and reduced beard growth. He had fathered three healthy children. He admitted to previous use of veterinary anabolic steroids up until 2 years ago. He had normal secondary sexual characteristics, no features of pituitary hypersecretion, normal visual fields but reduced testicular volumes (8 ml).Biochemical investigation showed growth ho...

In recent years, there is increased interest in using maggot debridement therapy (MDT) for ulcer treatment. MDT has shown beneficial effects on ulcers’ rate of healing, need for surgical intervention, and number of antibiotic-free days. In this retrospective study, we looked into the effects of MDT on the length of inpatient stay and need for surgical intervention.Data were collected from 33 randomly selected patients admitted into hospital with pri...

IntroductionMilk-Alkali Syndrome is defined by the triad of hypercalcaemia, acute renal failure and metabolic alkalosis. It was first described by Sippy in 1915 after people were treated with the Sippy regimen for peptic ulcer disease.Case reportA 76 year old woman was referred to the Endocrinology Clinic after she was initially presented to the Gastroenterolgy team with altered bowel habits, hypercalcaemia (...